{"id":1601,"date":"2023-03-16T12:06:55","date_gmt":"2023-03-16T11:06:55","guid":{"rendered":"https:\/\/portale2.unime.it\/modelloricerca\/?post_type=staffs&p=1601"},"modified":"2025-02-26T12:28:52","modified_gmt":"2025-02-26T11:28:52","slug":"carlo-bianchi","status":"publish","type":"staffs","link":"https:\/\/portale2.unime.it\/desylab\/staffs\/carlo-bianchi\/","title":{"rendered":"Salvatore Vincenzo Giofr\u00e8"},"content":{"rendered":"\t\t
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PROF. SALVATORE VINCENZO GIOFRE'


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Il Prof. Salvatore Vincenzo Giofr\u00e8 <\/strong>si \u00e8 laureato cum laude <\/em>in Chimica e Tecnologia Farmaceutiche presso l\u2019Universit\u00e0 di Messina nel 2005. Ha conseguito il titolo di Dottore di Ricerca in \u201cScienze Farmaceutiche\u201d nel 2009.<\/span><\/p>\n

Il Prof. Giofr\u00e8 \u00e8 Professore Associato per il SSD CHIM\/06 (Chimica Organica) presso il Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali dell\u2019Universit\u00e0 degli Studi di Messina.<\/span><\/p>\n

Fa parte del collegio dei docenti del Dottorato in \u201cScienze Chimiche\u201d presso l\u2019Universit\u00e0 di Messina.<\/span><\/p>\n

Dal 2020 \u00e8 docente di Chimica Organica del Corso di Laurea Triennale in Biotecnologie presso il Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali dell’Universit\u00e0 di Messina.<\/span><\/p>\n

E’ stato docente di Chimica Organica <\/em>del Corso di Laurea Triennale in Scienze Farmaceutiche Applicate e Prodotti per la Salute, Chimica Organica Superiore <\/em>e Metodi Fisici in Chimica Organica <\/em>del Corso di Laurea Magistrale in Chimica e Tecnologia Farmaceutiche, Laboratorio di <\/em>Chimica Organica I <\/em>del Corso di Laurea Triennale in Chimica e Chimica Verde<\/em> <\/span>del Corso di Laurea Magistrale in Chimica<\/span>.<\/span><\/p>\n

Fa parte dell’Accademia Peloritana dei Pericolanti<\/a><\/span><\/span><\/p>\n

E’ membro dell’Editorial Board Atti Della Accademia Peloritana dei Pericolanti<\/em> – Classe di Scienze Medico-Biologiche.<\/span><\/p>\n

E’ membro dell’Editorial Board di Letters in Organic Chemistry, <\/em>ISSN: 1875-6255 Online, ISSN: 1570-1786. Organics, MDPI<\/em>, ISSN 2673-401X.<\/span><\/p>\n

E’ Review Editor, Frontiers in Chemistry<\/em>, ISSN: 2296-2646 Online.<\/span><\/p>\n

E’ stato Guest Editor Special Issue: New Synthetic Method: Current Opinion in Green and Sustainable Chemistry, <\/em>Elsevier.<\/span><\/p>\n

E’ stato Membro del Comitato Organizzatore <\/span>VI Italian Spanish Symposium on Organic Chemistry<\/em>. Capo Taormina Hotel, Taormina dal 14-07-2006 al 17-07-2006. <\/span>Membro del Comitato Organizzatore XXXII Convegno Nazionale della Divisione di Chimica Organica della Societ\u00e0 Chimica Italiana<\/em>. Capo Taormina Hotel, Taormina, Italia dal 26-07-2008 al 30-07-2008. Membro del Comitato Organizzatore <\/span>XX Symposium \u201cScientific Days of the Consortium CINMPIS\u201d<\/em>. Microsoft Teams 7-8 settembre 2021. <\/span>Membro del Comitato Organizzatore XIX Convegno Nazionale sulle Reazioni Pericicliche e Sintesi di Etero e Carbocicli<\/em>, Reggio Calabria il 29-30 giugno 2023.<\/span><\/p>\n

Il Prof. Giofr\u00e8 \u00e8 ad oggi autore di 90 pubblicazioni su riviste internazionali citate pi\u00f9 di 2400 volte con H index = 30, con un I.F. totale maggiore di 300 e un I.F. medio per pubblicazione di circa 4 (Fonte Scopus e Isiweb Gennaio 2025), 1 brevetto, 2 capitoli di libro e numerose partecipazioni a convegno nazionali ed internazionali. La sua attivit\u00e0 scientifica riguarda principalmente le diverse metodologie della sintesi organica, la chimica dei composti eterociclici, le reazioni pericicliche, la chimica degli intermedi reattivi e dei meccanismi di reazione, per applicazioni in ambito farmaceutico e della chimica dei materiali.<\/span><\/p>\n

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PUBBLICAZIONI<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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  • Sar\u00e0, M., Giofr\u00e8, S.V.<\/strong>, Abate, S., Trapani, M., Verduci, R., D\u2019Angelo, G., Castriciano, M.A., Romeo, A., Neri, G., Mons\u00f9 Scolaro, L. Absorption and Fluorescence Emission Investigations on Supramolecular Assemblies of Tetrakis-(4-sulfonatophenyl)porphyrin and Graphene Quantum Dots. Molecules<\/em>, 2024<\/strong>, 29<\/em> (9), art. no. 2015. DOI: 10.3390\/molecules29092015<\/span><\/li>
  • Chiacchio, M.A., Campisi, A., Iannazzo, D., Giofr\u00e8, S.V.<\/strong>, Legnani, L. Design of New Schiff Bases and Their Heavy Metal Ion Complexes for Environmental Applications: A Molecular Dynamics and Density Function Theory Study. International Journal of Molecular Sciences<\/em>, 2024<\/strong>, 25<\/em> (8). DOI: 10.3390\/ijms25084159<\/span><\/li>
  • Romeo, R., Legnani, L., Chiacchio, M.A., Giofr\u00e9, S.V.<\/strong>, Iannazzo, D. Antiviral Compounds to Address Influenza Pandemics: An Update from 2016-2022. Current Medicinal Chemistry<\/em>, 2024<\/strong>, 31 (18), 2507-2549. DOI: 10.2174\/0929867331666230907093501<\/span><\/li>
  • Iannazzo, D., Celesti, C., Giofr\u00e8, S.V.<\/strong>, Ettari, R., Bitto, A. Theranostic Applications of 2D Graphene-Based Materials for Solid Tumors Treatment. Nanomaterials<\/em>, 2023<\/strong>, 13 (16), art. no. 2380. DOI: 10.3390\/nano13162380<\/span><\/li>
  • Iannazzo, D., Giofr\u00e9, S.V. Editorial overview: New synthetic methods: How chemistry change course for a sustainable future. Current Opinion in Green and Sustainable Chemistry<\/em>, 2023<\/strong>, 41<\/em>, art. no. 100828. DOI: 10.1016\/j.cogsc.2023.100828<\/span><\/li>
  • Smeriglio, A., Iraci, N., Denaro, M., Mandalari, G., Giofr\u00e8, S.V.<\/strong>, Trombetta, D. Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent. Antioxidants<\/em>, 2023<\/strong>, 12 <\/em>(4), art. no. 972. DOI: 10.3390\/antiox12040972<\/span><\/li>
  • Giofr\u00e8, S.V.<\/strong>, Celesti, C., Mistretta, G., Tiecco, M. Affinity of deep eutectic solvents with aromatic molecules and aromatic nanostructures in chemical transformations. Current Opinion in Green and Sustainable Chemistry<\/em>, 2023, 40, art. no. 100779. DOI: 10.1016\/j.cogsc.2023.100779<\/span><\/li>
  • Iannazzo, D., Celesti, C., Espro, C., Ferlazzo, A., Giofr\u00e8, S.V.<\/strong>, Scuderi, M., Scalese, S., Gabriele, B., Mancuso, R., Ziccarelli, I., Visalli, G., Di Pietro, A. Orange-Peel-Derived Nanobiochar for Targeted Cancer Therapy. Pharmaceutics<\/em>, 2022<\/strong>, 14<\/em> (10), art. no. 2249. DOI: 10.3390\/pharmaceutics14102249<\/span><\/li>
  • Legnani, L., Giofr\u00e9, S.V.<\/strong>, Iannazzo, D., Celesti, C., Veltri, L., Chiacchio, M.A. Chemoselective Oxidation of Isoxazolidines with Ruthenium Tetroxide: A Successful Intertwining of Combined Theoretical and Experimental Data. Molecules<\/em>, 2022<\/strong>, 27<\/em> (17), art. no. 5390.DOI: 10.3390\/molecules27175390<\/span><\/li>
  • Chiacchio, M.A., Iannazzo, D., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Legnani, L. Ruthenium tetroxide oxidation of N-methyl-isoxazolidine: Computational mechanistic study. Arabian Journal of Chemistry<\/em>, 2022<\/strong>, 15 (9), art. no. 104063. DOI: 10.1016\/j.arabjc.2022.104063<\/span><\/li>
  • Iraci, N., Corsaro, C., Giofr\u00e8, S.V.<\/strong>, Neri, G., Mezzasalma, A.M., Vacalebre, M., Speciale, A., Saija, A., Cimino, F., Fazio, E. Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs. Biomolecules<\/em>, 2022<\/strong>, 12<\/em> (8), art. no. 1060. DOI: 10.3390\/biom12081060<\/span><\/li>
  • Celesti, C., Gervasi, T., Cicero, N., Giofr\u00e8, S.V.<\/strong>, Espro, C., Piperopoulos, E., Gabriele, B., Mancuso, R., Vecchio, G.L., Iannazzo, D. Titanium Surface Modification for Implantable Medical Devices with Anti-Bacterial Adhesion Properties. Materials<\/em>, 2022<\/strong>, 15<\/em> (9), art. no. 3283. DOI: 10.3390\/ma15093283<\/span><\/li>
  • Giofr\u00e8, S.V.<\/strong>, Tiecco, M., Ferlazzo, A., Romeo, R., Ciancaleoni, G., Germani, R., Iannazzo, D. Base-Free Copper-Catalyzed Azide-Alkyne Click Cycloadditions (CuAAc) in Natural Deep Eutectic Solvents as Green and Catalytic Reaction Media** European Journal of Organic Chemistry<\/em>, 2021 (34), 4777-4789. DOI: 10.1002\/ejoc.202100698<\/span><\/li>
  • Speciale, A., Muscar\u00e0, C., Molonia, M.S., Cimino, F., Saija, A., Giofr\u00e8, S.V. <\/strong>Silibinin as potential tool against SARS-Cov-2: In silico spike receptor-binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects. Phytotherapy Research<\/em>, 2021<\/strong>, 35<\/em> (8), 4616-4625. DOI: 10.1002\/ptr.7107<\/span><\/li><\/ul>
    • Giofr\u00e8, S.V.<\/strong>, Napoli, E., Iraci, N., Speciale, A., Cimino, F., Muscar\u00e0, C., Molonia, M.S., Ruberto, G., Saija, A. Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in-silico study through molecular docking and dynamics simulations. Computers in Biology and Medicine<\/em>, 2021, 134, art. no. 104538. DOI: 10.1016\/j.compbiomed.2021.104538<\/span><\/li>
    • Scimone, C., Alibrandi, S., Donato, L., Giofr\u00e8, S.V.<\/strong>, Rao, G., Sidoti, A., D’Angelo, R. Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin. Journal of Clinical Pharmacy and Therapeutics<\/em>, 2021<\/strong>, 46<\/em> (2), 304-309. DOI: 10.1111\/jcpt.13315<\/span><\/li>
    • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Chiacchio, M.A., Veltri, L., Celesti, C., Iannazzo, D. Synthesis and biological evaluation of 2,3,4-triaryl-1,2,4-oxadiazol-5-ones as p38 mapk inhibitors. Molecules<\/em>, 2021<\/strong>, 26 (6), art. no. 1745. DOI: 10.3390\/molecules26061745<\/span><\/li>
    • Giofr\u00e8, S.V.<\/strong>, Tiecco, M., Celesti, C., Patan\u00e8, S., Triolo, C., Gulino, A., Spitaleri, L., Scalese, S., Scuderi, M., Iannazzo, D. Eco-friendly 1,3-dipolar cycloaddition reactions on graphene quantum dots in natural deep eutectic solvent. Nanomaterials<\/em>, 2020<\/strong>, 10<\/em> (12), art. no. 2549, pp. 1-15. DOI: 10.3390\/nano10122549<\/span><\/li>
    • Iannazzo, D., Ettari, R., Giofr\u00e8, S.<\/strong>, Eid, A.H., Bitto, A. Recent advances in nanotherapeutics for multiple myeloma. Cancers<\/em>, 2020<\/strong>, 12<\/em> (11), art. no. 3144, 1-16. DOI: 10.3390\/cancers12113144<\/span><\/li>
    • Legnani, L., Iannazzo, D., Pistone, A., Celesti, C., Giofr\u00e8, S.<\/strong>, Romeo, R., Di Pietro, A., Visalli, G., Fresta, M., Bottino, P., Blanco, I., Chiacchio, M.A. Functionalized polyhedral oligosilsesquioxane (POSS) based composites for bone tissue engineering: Synthesis, computational and biological studies. RSC Advances<\/em>, 2020<\/strong>, 10<\/em> (19), 11325-11334. DOI: 10.1039\/d0ra01636e<\/span><\/li>
    • Pistone, A., Iannazzo, D., Celesti, C., Scolaro, C., Giofr\u00e9, S.V.<\/strong>, Romeo, R., Visco, A. Chitosan\/PAMAM\/Hydroxyapatite engineered drug release hydrogels with tunable rheological properties. Polymers<\/em>, 2020<\/strong>, 12<\/em> (4), art. no. 0754. DOI: 10.3390\/polym12040754<\/span><\/li>
    • Giofr\u00e8, S.V.<\/strong>, Mancuso, R., Araniti, F., Romeo, R., Iannazzo, D., Abenavoli, M.R., Gabriele, B. Microwave-Assisted Synthesis of Sulfurated Heterocycles with Herbicidal Activity: Reaction of 2-Alkynylbenzoic Acids with Lawesson’s Reagent. ChemPlusChem<\/em>, 2019<\/strong>, 84<\/em> (7), 942-950. DOI: 10.1002\/cplu.201900316<\/span><\/li>
    • Mancuso, R., Ferlazzo, N., De Luca, G., Amuso, R., Piccionello, A.P., Giofr\u00e8, S.V.<\/strong>, Navarra, M., Gabriele, B. Synthesis, computational evaluation and pharmacological assessment of acetylsalicylic esters as anti-inflammatory agents. Medicinal Chemistry Research<\/em>, 2019<\/strong>, 28 (3), 292-299. DOI: 10.1007\/s00044-018-02284-3<\/span><\/li>
    • Iannazzo, D., Pistone, A., Celesti, C., Triolo, C., Patan\u00e9, S., Giofr\u00e9, S.V.<\/strong>, Romeo, R., Ziccarelli, I., Mancuso, R., Gabriele, B., Visalli, G., Facciol\u00e0, A., Di Pietro, A. A smart nanovector for cancer targeted drug delivery based on graphene quantum dots. Nanomaterials<\/em>, 2019<\/strong>, 9<\/em> (2), art. no. 282. DOI: 10.3390\/nano9020282<\/span><\/li>
    • Chiacchio, M.A., Lanza, G., Chiacchio, U., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Iannazzo, D., Legnani, L. Oxazole-based compounds as anticancer agents. Current Medicinal Chemistry<\/em>, 2019<\/strong>, 26<\/em> (41), 7337-7371. DOI: 10.2174\/0929867326666181203130402<\/span><\/li>
    • Chiacchio, M.A., Iannazzo, D., Romeo, R., Giofr\u00e8, S.V.<\/strong>, Legnani, L. Pyridine and pyrimidine derivatives as privileged scaffolds in biologically active agents. Current Medicinal Chemistry<\/em>, 2019<\/strong>, 26<\/em> (40), 7166-7195. DOI: 10.2174\/0929867325666180904125400<\/span><\/li><\/ul>
      • Chiacchio, M.A., Legnani, L., Campisi, A., Paola, B., Giuseppe, L., Iannazzo, D., Veltri, L., Giofr\u00e8, S.<\/strong>, Romeo, R. 1,2,4-Oxadiazole-5-ones as analogues of tamoxifen: Synthesis and biological evaluation. Organic and Biomolecular Chemistry<\/em>, 2019<\/strong>, 17<\/em> (19), 4892-4905. DOI: 10.1039\/c9ob00651f<\/span><\/li>
      • Romeo, R., Iannazzo, D., Veltri, L., Gabriele, B., Macchi, B., Frezza, C., Marino-Merlo, F., Giofr\u00e8, S.V.<\/strong> Pyrimidine 2,4-Diones in the design of new HIV RT inhibitors. Molecules<\/em>, 2019<\/strong>, 24<\/em> (9), art. no. 1718. DOI: 10.3390\/molecules24091718<\/span><\/li>
      • Zoccali, M., Giuffrida, D., Salafia, F., Giofr\u00e8, S.V.<\/strong>, Mondello, L. Carotenoids and apocarotenoids determination in intact human blood samples by online supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry. Analytica Chimica Acta<\/em>, 2018<\/strong>, 1032, 40-47. DOI: 10.1016\/j.aca.2018.06.022<\/span><\/li>
      • Smeriglio, A., Giofr\u00e8, S.V.<\/strong>, Galati, E.M., Monforte, M.T., Cicero, N., D’Angelo, V., Grassi, G., Circosta, C. Inhibition of aldose reductase activity by Cannabis sativa chemotypes extracts with high content of cannabidiol or cannabigerol. Fitoterapia<\/em>, 2018, 127, 101-108. DOI: 10.1016\/j.fitote.2018.02.002<\/span><\/li>
      • Cammilleri, G., Vazzana, M., Arizza, V., Giunta, F., Vella, A., Lo Dico, G., Giaccone, V., Giofr\u00e8, S.V.<\/strong>, Giangrosso, G., Cicero, N., Ferrantelli, V. Mercury in fish products: what\u2019s the best for consumers between bluefin tuna and yellowfin tuna? Natural Product Research<\/em>, 2018<\/strong>, 32<\/em> (4), 457-462. DOI: 10.1080\/14786419.2017.1309538<\/span><\/li>
      • Veltri, L., Giofr\u00e8, S.V.<\/strong>, Devo, P., Romeo, R., Dobbs, A.P., Gabriele, B. A Palladium Iodide-Catalyzed Oxidative Aminocarbonylation-Heterocyclization Approach to Functionalized Benzimidazoimidazoles. Journal of Organic Chemistry<\/em>, 2018<\/strong>, 83<\/em> (3), 1680-1685. DOI: 10.1021\/acs.joc.7b03167<\/span><\/li>
      • Romeo, R., Chiacchio, M.A., Campisi, A., Monciino, G., Veltri, L., Iannazzo, D., Broggini, G., Giofr\u00e8, S.V.<\/strong> Synthesis and biological evaluation of pyrimidine-oxazolidin-2-arylimino hybrid molecules as antibacterial agents. Molecules<\/em>, 2018<\/strong>, 23<\/em> (7), art. no. 1754. DOI: 10.3390\/molecules23071754<\/span><\/li>
      • Giuffrida, D., Zoccali, M., Giofr\u00e8, S.V., Dugo, P., Mondello, L. Apocarotenoids determination in Capsicum chinense Jacq. cv. Habanero, by supercritical fluid chromatography-triple-quadrupole\/mass spectrometry. Food Chemistry<\/em>, 2017<\/strong>, 231<\/em>, 316-323. DOI: 10.1016\/j.foodchem.2017.03.145<\/span><\/li>
      • Iannazzo, D., Pistone, A., Ziccarelli, I., Espro, C., Galvagno, S., Giofr\u00e9, S.V.<\/strong>, Romeo, R., Cicero, N., Bua, G.D., Lanza, G., Legnani, L., Chiacchio, M.A. Removal of heavy metal ions from wastewaters using dendrimer-functionalized multi-walled carbon nanotubes. Environmental Science and Pollution Research<\/em>, 2017<\/strong>, 24<\/em> (17), 14735-14747. DOI: 10.1007\/s11356-017-9086-2<\/span><\/li>
      • Trombetta, D., Smeriglio, A., Marcoccia, D., Giofr\u00e8, S.<\/strong>, Toscano, G., Mazzotti, F., Giovanazzi, A., Lorenzetti, S. Analytical evaluation and antioxidant properties of some secondary metabolites in northern Italian mono-and multi-varietal extra virgin olive oils (EVOOs) from early and late harvested olives. International Journal of Molecular Sciences<\/em>, 2017<\/strong>, 18<\/em> (4), art. no. 797, 14 p. DOI: 10.3390\/ijms18040797<\/span><\/li>
      • Iannazzo, D., Pistone, A., Salam\u00f2, M., Galvagno, S., Romeo, R., Giofr\u00e9, S.V.<\/strong>, Branca, C., Visalli, G., Di Pietro, A. Graphene quantum dots for cancer targeted drug delivery. International Journal of Pharmaceutics<\/em>, 2017<\/strong>, 518<\/em> (1-2), 185-192. DOI: 10.1016\/j.ijpharm.2016.12.060<\/span><\/li>
      • Mancuso, R., Pomelli, C.S., Raut, D.S., Marino, N., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Sartini, S., Chiappe, C., Gabriele, B. Copper-Catalyzed Recyclable Synthesis of (Z)-3-Alkylideneisoindolinones by Cycloisomerization of 2-Alkynylbenzamides in Ionic Liquids. ChemistrySelect<\/em>, 2017<\/strong>, 2<\/em> (3), 894-899. DOI: 10.1002\/slct.201601738<\/span><\/li><\/ul>
        • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Chiacchio, M.A. Synthesis and biological activity of unnatural enediynes. Current Medicinal Chemistry<\/em>, 2017<\/strong>, 24<\/em> (32), 1-57. DOI: 10.2174\/0929867324666170425095719<\/span><\/li>
        • Giofr\u00e8, S.V.<\/strong>, Cirmi, S., Mancuso, R., Nicol\u00f2, F., Lanza, G., Legnani, L., Campisi, A., Chiacchio, M.A., Navarra, M., Gabriele, B., Romeo, R. Synthesis of spiro[isoindole-1,5\u2032-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction. Beilstein Journal of Organic Chemistry<\/em>, 2016<\/strong>, 12<\/em>, 2793-2807. DOI: 10.3762\/bjoc.12.278<\/span><\/li>
        • Corsaro, C., Cicero, N., Mallamace, D., Vasi, S., Naccari, C., Salvo, A., Giofr\u00e8, S.V.<\/strong>, Dugo, G. HR-MAS and NMR towards Foodomics. Food Research International<\/em>, 2016<\/strong>, 89<\/em>, 1085-1094. DOI: 10.1016\/j.foodres.2016.09.033<\/span><\/li>
        • Chiacchio, M.A., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Romeo, G., Chiacchio, U. Isoxazolidines as biologically active compounds. Current Organic Synthesis<\/em>, 2016<\/strong>, 13<\/em> (5), 726-749. DOI: 10.2174\/1570179412666150914195807<\/span><\/li>
        • Legnani, L., Toma, L., Caramella, P., Chiacchio, M.A., Giofr\u00e8, S.<\/strong>, Delso, I., Tejero, T., Merino, P. Computational Mechanistic Study of Thionation of Carbonyl Compounds with Lawesson’s Reagent. Journal of Organic Chemistry<\/em>, 2016<\/strong>, 81<\/em> (17), 7733-7740. DOI: 10.1021\/acs.joc.6b01420<\/span><\/li>
        • Vadal\u00e0, R., Mottese, A.F., Bua, G.D., Salvo, A., Mallamace, D., Corsaro, C., Vasi, S., Giofr\u00e8, S.V.<\/strong>, Alfa, M., Cicero, N., Dugo, G. Statistical analysis of mineral concentration for the geographic identification of garlic samples from sicily (Italy), Tunisia and Spain. Foods<\/em>, 2016<\/strong>, 5<\/em> (1), art. no. 20, 1-11. DOI: 10.3390\/foods5010020<\/span><\/li>
        • Chiacchio, U., Broggini, G., Romeo, R., Gazzola, S., Chiacchio, M.A., Giofr\u00e8, S.V.<\/strong>, Gabriele, B., Mancuso, R., Floresta, G., Zagni, C. Intramolecular oxidative palladium-catalyzed diamination reactions of alkenyl sulfamates: An efficient synthesis of [1,2,5]thiadiazolo-fused piperazinones. RSC Advances<\/em>, 2016<\/strong>, 6<\/em> (62), 57521-57529. DOI: 10.1039\/c6ra13141g<\/span><\/li>
        • Giofr\u00e8, S.V.<\/strong>, Romeo, R., Mancuso, R., Cicero, N., Corriero, N., Chiacchio, U., Romeo, G., Gabriele, B. A new microwave-assisted thionation-heterocyclization process leading to benzo[c]thiophene-1(3H)-thione and 1H-isothiochromene-1-thione derivatives. RSC Advances<\/em>, 2016<\/strong>, 6<\/em> (25), 20777-20780. DOI: 10.1039\/c6ra01329e<\/span><\/li>
        • Giofr\u00e8, S.V.<\/strong>, Romeo, R., Garozzo, A., Cicero, N., Campisi, A., Lanza, G., Chiacchio, M.A. 5-(3-phosphonated 1H-1,2,3-triazol-4-yl)isoxazolidines: Synthesis, DFT studies and biological properties. Arkivoc,<\/em> 2015<\/strong>, (7), 253-269.DOI: 10.3998\/ark.5550190.p009.353<\/span><\/li>
        • Iannazzo, D., Pistone, A., Visco, A., Galtieri, G., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Romeo, G., Cappello, S., Bonsignore, M., Denaro, R., Galvagno, S. 1,2,3-Triazole\/MWCNT conjugates as filler for gelcoat nanocomposites: New active antibiofouling coatings for marine application. Materials Research Express<\/em>, 2015<\/strong>, 2<\/em> (11), art. no. 115001. DOI: 10.1088\/2053-1591\/2\/11\/115001<\/span><\/li>
        • Pant\u00f2, S., Sciarrone, D., Maimone, M., Ragonese, C., Giofr\u00e8, S.<\/strong>, Donato, P., Farnetti, S., Mondello, L. Performance evaluation of a versatile multidimensional chromatographic preparative system based on three-dimensional gas chromatography and liquid chromatography-two-dimensional gas chromatography for the collection of volatile constituents. Journal of Chromatography A<\/em>, 2015<\/strong>, 1417<\/em>, 96-103. DOI: 10.1016\/j.chroma.2015.09.039<\/span><\/li>
        • Cicero, N., Corsaro, C., Salvo, A., Vasi, S., Giofr\u00e9, S.V., Ferrantelli, V., Di Stefano, V., Mallamace, D., Dugo, G. The metabolic profile of lemon juice by proton HR-MAS NMR: The case of the PGI Interdonato Lemon of Messina. Natural Product Research<\/em>, 2015<\/strong>, 29<\/em> (20), 1894-1902. DOI: 10.1080\/14786419.2015.1012166<\/span><\/li><\/ul>
          • Sorrenti, V., Vanella, L., Acquaviva, R., Cardile, V., Giofr\u00e8, S.<\/strong>, Di Giacomo, C. Cyanidin induces apoptosis and differentiation in prostate cancer cells. International Journal of Oncology<\/em>, 2015<\/strong>, 47<\/em> (4), 1303-1310. DOI: 10.3892\/ijo.2015.3130<\/span><\/li>
          • Araniti, F., Mancuso, R., Lupini, A., Giofr\u00e8, S.V.<\/strong>, Sunseri, F., Gabriele, B., Abenavoli, M.R. Phytotoxic potential and biological activity of three synthetic coumarin derivatives as new natural-like herbicides. Molecules<\/em>, 2015<\/strong>, 20<\/em> (10), 17883-17902. DOI: 10.3390\/molecules201017883<\/span><\/li>
          • Giofr\u00e8, S.V.<\/strong>, Romeo, R., Chiacchio, U., Romeo, G., Chiacchio, M.A. Phosphonated n,o-nucleosides: Synthesis and biological evaluation. Mini-Reviews in Organic Chemistry<\/em>, 2015<\/strong>, 12<\/em> (3), 249-257. DOI: 10.2174\/1570193×1203150429104924<\/span><\/li>
          • Miroddi, M., Navarra, M., Calapai, F., Mancari, F., Giofr\u00e8, S.V.<\/strong>, Gangemi, S., Calapai, G. Review of clinical pharmacology of Aloe vera L. in the treatment of psoriasis. Phytotherapy Research<\/em>, 2015<\/strong>, 29 (5), 648-655. DOI: 10.1002\/ptr.5316<\/span><\/li>
          • Giofr\u00e8, S.V.<\/strong>, Romeo, R., Carnovale, C., Mancuso, R., Cirmi, S., Navarra, M., Garozzo, A., Chiacchio, M.A. Synthesis and biological properties of 5-(1H-1,2,3-triazol-4-yl)isoxazolidines: A new class of C-nucleosides. Molecules<\/em>, 2015<\/strong>, 20<\/em> (4), 5260-5275. DOI: 10.3390\/molecules20045260<\/span><\/li>
          • Romeo, R., Carnovale, C., Giofr\u00e8, S.V.<\/strong>, Chiacchio, M.A., Garozzo, A., Amata, E., Romeo, G., Chiacchio, U. C-5′-Triazolyl-2′-oxa-3′-aza-4’a-carbanucleosides: Synthesis and biological evaluation. Beilstein Journal of Organic Chemistry<\/em>, 2015<\/strong>, 11<\/em>, 328-334. DOI: 10.3762\/bjoc.11.38<\/span><\/li>
          • Macchi, B., Romeo, G., Chiacchio, U., Frezza, C., Giofr\u00e8, S.V.<\/strong>, Marino-Merlo, F., Mastino, A. Phosphonated nucleoside analogues as antiviral agents. Topics in Medicinal Chemistry<\/em>, 2015<\/strong>, 15<\/em>, 53-92. DOI: 10.1007\/7355_2013_28<\/span><\/li>
          • Rescifina, A., Zagni, C., Mineo, P.G., Giofr\u00e8, S.V.<\/strong>, Chiacchio, U., Tommasone, S., Talotta, C., Gaeta, C., Neri, P. DNA recognition with polycyclic-aromatic-hydrocarbon-presenting calixarene conjugates. European Journal of Organic Chemistry<\/em>, 2014<\/strong>, (34), 7605-7613. DOI: 10.1002\/ejoc.201403050<\/span><\/li>
          • Trombetta, D., Giofre, S.V.<\/strong>, Tomaino, A., Raciti, R., Saija, A., Cristani, M., Romeo, R., Siracusa, L., Ruberto, G. Selective COX-2 inhibitory properties of dihydrostilbenes from liquorice leaves-in vitro assays and structure\/activity relationship study. Natural Product Communications<\/em>, 2014<\/strong>, 9<\/em> (12), 1761-1764. DOI: 10.1177\/1934578×1400901226<\/span><\/li>
          • Romeo, R., Carnovale, C., Giofr\u00e8, S.V.<\/strong>, Monciino, G., Chiacchio, M.A., Sanfilippo, C., Macchi, B. Enantiomerically pure phosphonated carbocyclic 2\u2032-Oxa-3\u2032-azanucleosides: Synthesis and biological evaluation. Molecules<\/em>, 2014<\/strong>, 19<\/em> (9), 14406-14416. DOI: 10.3390\/molecules190914406<\/span><\/li>
          • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Carnovale, C., Chiacchio, M.A., Campisi, A., Mancuso, R., Cirmi, S., Navarra, M. Synthesis and Biological Activity of Triazole-Appended N,O-Nucleosides. European Journal of Organic Chemistry<\/em>, 2014<\/strong>, (25), 5442-5447. DOI: 10.1002\/ejoc.201402106<\/span><\/li>
          • Cimino, S., Favilla, V., Russo, G.I., Galvano, F., Li Volti, G., Barbagallo, I., Giofr\u00e8, S.V.<\/strong>, D’Orazio, N., Di Rosa, A., Madonia, M., Morgia, G. Oxidative stress and body composition in prostate cancer and benign prostatic hyperplasia patients. Anticancer Research<\/em>, 2014<\/strong>, 34<\/em> (9), 5051-5056.<\/span><\/li>
          • Bisignano, C., Filocamo, A., Ginestra, G., Giofre’, S.V.<\/strong>, Navarra, M., Romeo, R., Mandalari, G. 3,4-DHPEA-EA from Olea Europaea L. is effective against standard and clinical isolates of Staphylococcus sp. Annals of Clinical Microbiology and Antimicrobials<\/em>, 2014<\/strong>, 13<\/em> (1), art. no. 24. DOI: 10.1186\/1476-0711-13-24<\/span><\/li>
          • Romeo, R., Navarra, M., Giofr\u00e8, S.V., Carnovale, C., Cirmi, S., Lanza, G., Chiacchio, M.A. Synthesis and biological activity of new arenediyne-linked isoxazolidines. Bioorganic and Medicinal Chemistry<\/em>, 2014<\/strong>, 22<\/em> (13), 3379-3385. DOI: 10.1016\/j.bmc.2014.04.047<\/span><\/li>
          • Mancuso, R., Ziccarelli, I., Armentano, D., Marino, N., Giofr\u00e8, S.V.<\/strong>, Gabriele, B. Divergent palladium iodide catalyzed multicomponent carbonylative approaches to functionalized isoindolinone and isobenzofuranimine derivatives. Journal of Organic Chemistry<\/em>, 2014<\/strong>, 79<\/em> (8), 3506-3518. DOI: 10.1021\/jo500281h<\/span><\/li>
          • Giofr\u00e8, S.V.<\/strong>, Romeo, R., Chiacchio, M.A. Phosphonated isoxazolidinyl nucleosides, a new class of modified nucleosides. EuroMediterranean Biomedical Journal<\/em>, 2014<\/strong>, 9<\/em> (8), art. no. 7, 45-55. DOI: 10.3269\/1970-5492.2014.9.7<\/span><\/li>
          • Oliverio, M., Nardi, M., Costanzo, P., Cariati, L., Cravotto, G., Giofr\u00e8, S.V.<\/strong>, Procopio, A. Non-conventional methodologies in the synthesis of 1-indanones. Molecules<\/em>, 2014<\/strong>, 19<\/em> (5), 5599-5610. DOI: 10.3390\/molecules19055599<\/span><\/li>
          • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Carnovale, C., Campisi, A., Parenti, R., Bandini, L., Chiacchio, M.A. Synthesis and biological evaluation of 3-hydroxymethyl-5-(1H-1,2,3-triazol) isoxazolidines. Bioorganic and Medicinal Chemistry<\/em>, 2013<\/strong>, 21<\/em> (24), 7929-7937. DOI: 10.1016\/j.bmc.2013.10.001<\/span><\/li>
          • Romeo, R., Giofr\u00e8, S.V., Garozzo, A., Bisignano, B., Corsaro, A., Chiacchio, M.A. Synthesis and biological evaluation of furopyrimidine N,O-nucleosides. Bioorganic and Medicinal Chemistry<\/em>, 2013<\/strong>, 21<\/em> (18), 5688-5693. DOI: 10.1016\/j.bmc.2013.07.031<\/span><\/li>
          • Chiacchio, U., Corsaro, A., Giofr\u00e8, S.<\/strong>, Romeo, G. Isoxazolidinyl Nucleosides. Chemical Synthesis of Nucleoside Analogues, 2013<\/strong>, 781-818. DOI: 10.1002\/9781118498088.ch17<\/span><\/li>
          • Lanza, G., Chiacchio, M.A., Giofr\u00e8, S.V.<\/strong>, Romeo, R., Merino, P. The high selectivity of the Cp2<\/sub>ZrHCl reducing agent for imides: A combined experimental and theoretical study on \u03b3-lactam and isoxazolidinone derivatives. European Journal of Organic Chemistry<\/em>, 2013<\/strong>, (1), 95-104. DOI: 10.1002\/ejoc.201201186<\/span><\/li>
          • Romeo, R., Carnovale, C., Giofr\u00e8, S.V.<\/strong>, Romeo, G., MacChi, B., Frezza, C., Marino-Merlo, F., Pistar\u00e0, V., Chiacchio, U. Truncated phosphonated C-1\u2032-branched N,O-nucleosides: A new class of antiviral agents. Bioorganic and Medicinal Chemistry<\/em>, 2012<\/strong>, 20<\/em> (11), 3652-3657. DOI: 10.1016\/j.bmc.2012.03.047<\/span><\/li>
          • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Macchi, B., Balestrieri, E., Mastino, A., Merino, P., Carnovale, C., Romeo, G., Chiacchio, U. Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors. ChemMedChem<\/em>, 2012<\/em>, 7<\/em> (4), 565-569. DOI: 10.1002\/cmdc.201200022<\/span><\/li>
          • Piperno, A., Carnovale, C., Giofr\u00e8, S.V.<\/strong>, Iannazzo, D. Hydrozirconation of four-, five-, six- and seven-membered N-alkoxycarbonyl lactams to lactamols. Tetrahedron Letters<\/em>, 2011<\/strong>, 52<\/em> (51), 6880-6882. DOI: 10.1016\/j.tetlet.2011.10.006<\/span><\/li>
          • Romeo, R., Giofr\u00e8, S.V.<\/strong>, Iaria, D., Sciortino, M.T., Ronsisvalle, S., Chiacchio, M.A., Scala, A. Synthesis of 5-alkynyl isoxazolidinyl nucleosides. European Journal of Organic Chemistry<\/em>, 2011<\/strong>, (28), 5690-5695. DOI: 10.1002\/ejoc.201100767<\/span><\/li>
          • Ettari, R., Zappal\u00e0, M., Micale, N., Grazioso, G., Giofr\u00e8, S.<\/strong>, Schirmeister, T., Grasso, S. Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors. European Journal of Medicinal Chemistry<\/em>, 2011<\/strong>, 46<\/em> (6), 2058-2065. DOI: 10.1016\/j.ejmech.2011.02.058<\/span><\/li>
          • Balestrieri, E., Pizzimenti, F., Ferlazzo, A., Giofr\u00e8, S.V.<\/strong>, Iannazzo, D., Piperno, A., Romeo, R., Chiacchio, M.A., Mastino, A., Macchi, B. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorganic and Medicinal Chemistry<\/em>, 2011<\/strong>, 19<\/em> (6), 2084-2089. DOI: 10.1016\/j.bmc.2011.01.024<\/span><\/li><\/ul>
            • Iannazzo, D., Carnovale, C., Giofr\u00e8, S.V.<\/strong>, Ettari, R., Romeo, G., Romeo, R., Lanza, G., Chiacchio, U. Formation of 3-aminofuran-2-(5 H)-ones and 3-amino-1 H -pyrrole-2,5-diones by rearrangement of isoxazolidines. Synlett<\/em>, 2011<\/strong>, (2), art. no. G34710ST, 245-248. DOI: 10.1055\/s-0030-1259308<\/span><\/li>
            • Iannazzo, D., Brunaccini, E., Giofr\u00e8, S.V.<\/strong>, Piperno, A., Romeo, G., Ronsisvalle, S., Chiacchio, M.A., Lanza, G., Chiacchio, U. Competitive formation of \u03b2-enaminones and 3-amino-2(5H)-furanones from the isoxazolidine system: A combined synthetic and quantum chemical study. European Journal of Organic Chemistry<\/em>, 2010<\/strong>, (30), 5897-5905. DOI: 10.1002\/ejoc.201000579<\/span><\/li>
            • Piperno, A., Giofr\u00e8, S.V.<\/strong>, Iannazzo, D., Romeo, R., Romeo, G., Chiacchio, U., Rescifina, A., Piotrowska, D.G. Synthesis of C-4\u2032Truncated Phosphonated Carbocyclic 2\u2032-Oxa-3\u2032-azanucleosides as Antiviral Agents. Journal of Organic Chemistry<\/em>, 2010<\/strong>, 75<\/em> (9), 2798-2805. DOI: 10.1021\/jo902485m<\/span><\/li>
            • Romeo, G., Giofr\u00e9, S.V.<\/strong>, Piperno, A., Romeo, R., Chiacchiob, M.A. Synthesis of N,O-homonucleosides with high conformational freedom. Arkivoc, 2009 (8), 168-176. DOI: 10.3998\/ark.5550190.0010.814<\/span><\/li>
            • Piperno, A., Chiacchio, U., Iannazzo, D., Giofr\u00e8, S.V.<\/strong>, Romeo, G., Romeo, R. First example of direct RuO4- catalyzed oxidation of isoxazolidines to 3-isoxazolidones. Journal of Organic Chemistry<\/em>, 2007<\/strong>, 72<\/em> (10), 3958-3960. DOI: 10.1021\/jo070211n<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":2202,"template":"elementor_header_footer","class_list":["post-1601","staffs","type-staffs","status-publish","has-post-thumbnail","hentry","entry"],"yoast_head":"\nSalvatore Vincenzo Giofr\u00e8 - Desy Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/portale2.unime.it\/desylab\/staffs\/carlo-bianchi\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salvatore Vincenzo Giofr\u00e8 - Desy Lab\" \/>\n<meta property=\"og:description\" content=\"PROF. SALVATORE VINCENZO GIOFRE’ sgiofre@unime.it ID scopus: 16309695300 0906766566 Il Prof. Salvatore Vincenzo Giofr\u00e8 si \u00e8 laureato cum laude in Chimica e Tecnologia Farmaceutiche presso l\u2019Universit\u00e0 di Messina nel 2005. Ha conseguito il titolo di Dottore di Ricerca in \u201cScienze Farmaceutiche\u201d nel 2009. 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